Scientist - Analytical Development and Operations
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Employment type:
Full time
Experience required:
Intermediate
Salary
Salary not provided
About the company:
ABOUT GREENLIGHT
At GreenLight we are working to solve two of the world's greatest problems: global food insecurity and equal access to vaccines and the associated health benefits. Unlike most corporations who can be required to put profits ahead of other principles, GreenLight is one of the first Public Benefit Corporations to be publicly traded and have a charter that requires a focus on how it benefits its employees, community and society and has a broad portfolio addressing key issues in plant health and human health (Nasdaq: GRNA) by leveraging the full potential of dsRNA and mRNA. The GreenLight team is over 300 people across our headquarters in Medford, MA, an R&D facility in Woburn, MA and an R&D facility in Research Triangle Park, NC. GreenLight also has a biomanufacturing plant in Rochester, NY. Initiatives include finding ways to support biodiversity, protect bees and other pollinators, treat rare diseases as well as develop vaccines.
At GreenLight, we believe inclusion is the way forward. We celebrate the power of working together to address humanity’s challenges, meet the needs of underserved populations, and push the boundaries of scientific discovery. Fueled by our aspiration for a true sense of belonging, our talented teams embody the principles of diversity and equality as we strive to bring food security, medicine, and healthcare to everyone—paving the way for a sustainable future. For more information, visit www.greenlightbio.com.
POSITION SUMMARY
GreenLight Biosciences is seeking a highly motivated and collaborative scientist to join the Analytical Development team. This role is an exciting opportunity to support development of new LNP-mRNA vaccine candidates to help advance the company’s pipeline and RNA platform technology. The incumbent will use expertise in early and late stage/commercial development to develop, qualify, and support analytical assays. The successful candidate will also help expand analytical assay capabilities and build standardized procedures and new platforms.
MAJOR RESPONSIBILITIES
- Develop quantitative assays for critical quality attributes by high-resolution mass spectrometry.
- Develops, qualifies, and transfers a range of analytical assays to support early- and late-stage projects.
- Independently works on assay method development, participates in method qualifications/transfers, performs analytical testing of RNA vaccines and therapeutics in a variety of matrices.
- Mentors, trains, and coordinates laboratory activities of junior team members in reference to assigned projects and assists in troubleshooting instruments and analytical problems.
- Reviews technical data for completeness and correctness. Performs self-review and peer review of the data ensuring compliance with applicable SOPs.
- Delivers timely and impactful data to help build process and product knowledge to meet project milestones and associated regulatory requirements; this includes the design of protocols, execution of experiments, and reporting and documenting data in technical reports.
- Communicates data and technical issues to internal stakeholders and responds to partner needs and questions.
- Authors, reviews and approves documents including SOPs and method development reports. Presents results and research at team meetings
- Processes data with appropriate statistical analysis and delivers experimental reports and data summaries to multidisciplinary teams.
- Stays up to date with scientific and technical development literature within the fields of analytical chemistry and bioanalytical chemistry.
- Contributes to creation and writing of standardized protocols
PROFESSIONAL EXPERIENCE / QUALIFICATIONS
- 4+ years of experience, preferably in an analytical chemistry group at an industrial biotechnology company; relevant graduate research will also be considered
- Hands-on experience with mass spectrometry is required
- Strong background in chemistry, with knowledge of nucleic acid chemistry, biochemistry, and microbial metabolism a plus
- Method development experience, with a proven track record of successfully developing sample extraction methods and robust, specific LC quantification assays is required
- Experience with nucleotide and oligonucleotide research is required
- Familiarity with diverse analytical techniques for metabolite detection/quantification
- Able to perform successfully under pressure while prioritizing and handling multiple projects or activities
- Experience documenting experimental results and instrument performance in laboratory notebooks and electronic databases
- Must be highly motivated with high quality standards for one’s own work, strong communication skills, and an absolute commitment to team success
EDUCATION
- Ph.D. or M.S. in analytical chemistry, chemistry, biochemistry, chemical engineering, or related field
Greenlight Biosciences Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
GreenLight requires proof of COVID-19 vaccination for its employees.
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