Research Associate - Method Development and Operations
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Employment type:
Full time
Experience required:
Intermediate
Salary
Salary not provided
About the company:
ABOUT GREENLIGHT
At GreenLight we are working to solve two of the world's greatest problems: global food insecurity and equal access to vaccines and the associated health benefits. Unlike most corporations who can be required to put profits ahead of other principles, GreenLight is one of the first Public Benefit Corporations to be publicly traded and have a charter that requires a focus on how it benefits its employees, community and society and has a broad portfolio addressing key issues in plant health and human health (Nasdaq: GRNA) by leveraging the full potential of dsRNA and mRNA. The GreenLight team is over 300 people across our headquarters in Medford, MA, an R&D facility in Woburn, MA and an R&D facility in Research Triangle Park, NC. GreenLight also has a biomanufacturing plant in Rochester, NY. Initiatives include finding ways to support biodiversity, protect bees and other pollinators, treat rare diseases as well as develop vaccines.
At GreenLight, we believe inclusion is the way forward. We celebrate the power of working together to address humanity’s challenges, meet the needs of underserved populations, and push the boundaries of scientific discovery. Fueled by our aspiration for a true sense of belonging, our talented teams embody the principles of diversity and equality as we strive to bring food security, medicine, and healthcare to everyone—paving the way for a sustainable future. For more information, visit www.greenlightbio.com.
POSITION SUMMARY
GreenLight Biosciences is seeking a highly motivated research associate or senior research associate to join the Analytical Development team. This role is an exciting opportunity to support development of new LNP-mRNA vaccine candidates to help advance the company’s pipeline and RNA platform technology. The research associate will work closely with the multiple organizations within the company, performing a range of analytical assays to quantify and characterize analytes. Responsibilities include development and execution of sample extraction methods, HPLC, LC-MS, IC, & CE methods, along with corresponding data analysis. Strong technical, organizational, and communication skills, along with a commitment to excellence and high-quality work are required.
MAJOR RESPONSIBILITIES
- Execute analytical testing that supports several activities in both early- and late-stage development
- Operate and maintain analytical instrumentation, including HPLC/UPLC/IC systems, QQQ and high-resolution mass spectrometers, high-throughput capillary electrophoresis systems, and automated liquid handlers
- Review and deliver reports to multidisciplinary R&D team members
- Track assay performance: execute detail-oriented data mining, trending, and statistical evaluation to assess assay performance and data integrity
- Analyze, summarize, and present experimental results to manager and other team members
- Work collaboratively with other R&D team members to accomplish project goals and milestones
- Use creative problem-solving skills to troubleshoot experimental challenges
- Apply DOE methodology to optimize assays for minimal CV and increased reproducibility
- Ensure accuracy of data and timely turnaround of results coming out of the group
- Analyze, summarize, and present technical data to manager and other team members
- Work collaboratively with other R&D team members to accomplish project goals and milestones
- Stay up to date with scientific and technical development within the field of analytical chemistry
- Detail-oriented tracking and documenting of experimental results and instrument performance in electronic laboratory notebooks and company databases.
PROFESSIONAL EXPERIENCE / QUALIFICATIONS
- Strong background in chemistry, with knowledge of nucleic acid chemistry, biochemistry, and microbial metabolism a plus
- Method development experience, with a proven track record of successfully developing sample extraction methods and robust, specific LC quantification assays
- Experience with nucleotide and oligonucleotide / nucleic acid separations is preferred
- Familiarity with diverse analytical techniques for metabolite detection/quantification
- Hands on experience troubleshooting analytical equipment is a plus
- Experience with Mass Spectrometry is a plus
- Must be highly motivated with high quality standards for one’s own work, strong communication skills, and an absolute commitment to team success
EDUCATION
- B.S. or M.S. in analytical chemistry, chemistry, biochemistry, chemical engineering, or related field
- 2+ years’ experience for M.S and 4+ years’ experience for B.S., preferably in an analytical chemistry group at an industrial biotechnology company; relevant graduate research will be considered
Greenlight Biosciences Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
GreenLight requires proof of COVID-19 vaccination for its employees.
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