Scientist, Delivery Technology
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Employment type:
Full time
Experience required:
Intermediate
Salary
Salary not provided
About the company:
ABOUT GREENLIGHT
At GreenLight we are working to solve two of the world's greatest problems: global food insecurity and equal access to vaccines and the associated health benefits. Unlike most corporations who can be required to put profits ahead of other principles, GreenLight is one of the first Public Benefit Corporations to be publicly traded and have a charter that requires a focus on how it benefits its employees, community and society and has a broad portfolio addressing key issues in plant health and human health (Nasdaq: GRNA) by leveraging the full potential of dsRNA and mRNA. The GreenLight team is a little over 260 people across our headquarters in Lexington, MA, an R&D facility and an R&D facility in Research Triangle Park, NC. GreenLight also has a biomanufacturing plant in Rochester, NY. Initiatives include finding ways to support biodiversity, protect bees and other pollinators, treat rare diseases as well as develop vaccines.
At GreenLight, we believe inclusion is the way forward. We celebrate the power of working together to address humanity’s challenges, meet the needs of underserved populations, and push the boundaries of scientific discovery. Fueled by our aspiration for a true sense of belonging, our talented teams embody the principles of diversity and equality as we strive to bring food security, medicine, and healthcare to everyone—paving the way for a sustainable future. For more information, visit www.greenlightbio.com.
GreenLight Biosciences is seeking an exceptional, highly motivated, and collaborative Scientist to join the Formulations team - Delivery Technology function. The candidate will be focused on the development of novel delivery technology approaches to bring a higher concentration of dsRNA to the target site-of-action. The successful candidate will provide well-characterized solutions to enable application of dsRNA to new targets. The tools developed will be designed to improve the uptake and mode-of-action of RNAi. Experience with macromolecule delivery in biologic systems is required. Experience with nanoparticle formation and characterization techniques is required. Familiarity with a variety of analytical techniques including DLS, electrophoresis (gel and capillary), HPLC, SEC, Spectroscopy (FTIR, Raman, Fluorescence) applied to oligonucleotide characterization is required. Strong technical, organizational, and communication skills, along with a commitment to excellence and high-quality work are required. The individual will contribute within an innovative and fast-paced R&D environment and help to build the future of RNA revolution. Come and join us.
Responsibilities:
- Design and prepare delivery technologies that increase the concentration of dsRNA at the target site of action.
- Characterize novel formulations of dsRNA and formulation components in complex matrix systems.
- Analyze, summarize, and clearly present technical data to the rest of the R&D organization and in external venues
- Work collaboratively with other R&D team members to accomplish project goals and milestones
Qualifications:
- BS, MS and/or PhD in chemistry, pharmacology, biochemistry, chemical engineering, or related field
- 5-10+ years’ experience, preferably in a drug delivery, pharmacology or biochemistry of macromolecules in an industry-applied laboratory setting
- Experience with the design of macromolecule delivery systems into cell-based and biological-systems-based assays; specifically experience with lipid nanoparticle, polymer encapsulation and inorganic particle delivery methods is needed
- Experience successfully managing complex experimental design across cross-functional teams
- Experience with biologic or chemical plant health products and bioassays
- Experience with oligonucleotide delivery is preferred
- Experience with microscopic characterization of different colloidal systems through different analytical techniques, including DLS, Zeta Potential, etc. as well as definition of their macroscopic physical attributes such as viscosity and surface tension, is preferred
- Must be highly motivated with high quality standards and an absolute commitment to team success
- Ability to work effectively in fast-paced R&D environment with multiple tasks at hand
- Strong communication and organizational skills, with a proven ability to convey complex ideas in a clear, precise, and actionable manner
Greenlight Biosciences Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
GreenLight requires proof of COVID-19 vaccination for its employees.
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