Research Associate - Method Development and Operations
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Employment type:
Full time
Experience required:
Intermediate
Salary
Salary not provided
About the company:
ABOUT GREENLIGHT
At GreenLight we are working to solve two of the world's greatest problems: global food insecurity and equal access to vaccines and the associated health benefits. Unlike most corporations who can be required to put profits ahead of other principles, GreenLight is one of the first Public Benefit Corporations to be publicly traded and have a charter that requires a focus on how it benefits its employees, community and society and has a broad portfolio addressing key issues in plant health and human health (Nasdaq: GRNA) by leveraging the full potential of dsRNA and mRNA. The GreenLight team is over 300 people across our headquarters in Medford, MA, an R&D facility in Woburn, MA and an R&D facility in Research Triangle Park, NC. GreenLight also has a biomanufacturing plant in Rochester, NY. Initiatives include finding ways to support biodiversity, protect bees and other pollinators, treat rare diseases as well as develop vaccines.
At GreenLight, we believe inclusion is the way forward. We celebrate the power of working together to address humanity’s challenges, meet the needs of underserved populations, and push the boundaries of scientific discovery. Fueled by our aspiration for a true sense of belonging, our talented teams embody the principles of diversity and equality as we strive to bring food security, medicine, and healthcare to everyone—paving the way for a sustainable future. For more information, visit www.greenlightbio.com.
POSITION SUMMARY
GreenLight Biosciences is seeking a highly motivated research associate or senior research associate to join the Analytical Development team. This role is an exciting opportunity to support development of new LNP-mRNA vaccine candidates to help advance the company’s pipeline and RNA platform technology. The research associate will work closely with multiple organizations within the company, performing a range of analytical assays to quantify and characterize analytes. Responsibilities include development and execution of sample extraction methods, HPLC, LC-MS, IC, & CE methods, along with corresponding data analysis. Strong technical, organizational, and communication skills, along with a commitment to excellence and high-quality work are required.
MAJOR RESPONSIBILITIES
- Utilize analytical methods to determine purity, content, impurities & related substances of raw/starting materials, in-process samples, drug substance, and drug product
- Carry-out matrix interference and troubleshooting experiments to ensure assay accuracy, reproducibility, and precision, while working independently and with guidance from supervisor
- Support raw material de-risking as well as drug substance and drug product impurity characterization and identification
- Adapt existing analytical procedures and participate in new technology on-boarding from early discovery and CMC development teams
- Perform assays transferred from method development teams, and optimize current methods
- Generate quality analytical data, ensuring record completeness and accuracy
- Report results and conclusions both orally and in writing to team lead and process teams
- Stay up-to-date on analytical methodology, techniques and concepts through literature review and external workshops
- Organize efficient testing workflows and laboratory operations
- Highly motivated self-starter and collaborative team member, motivated to achieve business objectives
PROFESSIONAL EXPERIENCE / QUALIFICATIONS
- Hands-on experience with a variety of analytical and biochemistry techniques, including but not limited to PCR, ELISA, HPLC, CE, plate-based assays, content determination (e.g., QuantiT, Ribogreen), and particle analysis by DLS
- Proven track record of delivering high quality reproducible assay results in support of process development
- Knowledge and experience working in a regulated pharmaceutical or biotech environment, specifically within Analytical Development or QC
- Background in analytical chemistry, with knowledge of nucleic acid properties is a plus
- Ability to carry out work independently in a fast-paced environment, with attention to detail
- Team-player with high energy, immense desire for learning and interest to contribute to various programs
- Effective collaboration, communication, and commitment to timelines
EDUCATION
- M,S. with 1-2 years of industry experience, or
- B.S. with 2-3 years of industry experience
Greenlight Biosciences Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
GreenLight requires proof of COVID-19 vaccination for its employees.
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